A Model for the Transient Subdiffusive Behavior of Particles in Mucus.
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Authors
Ernst, MatthiasJohn, Thomas
Guenther, Marco
Wagner, Christian
Schaefer, Ulrich F
Lehr, Claus-Michael
Issue Date
2017-01-10
Metadata
Show full item recordAbstract
In this study we have applied a model to explain the reported subdiffusion of particles in mucus, based on the measured mean squared displacements (MSD). The model considers Brownian diffusion of particles in a confined geometry, made from permeable membranes. The applied model predicts a normal diffusive behavior at very short and long time lags, as observed in several experiments. In between these timescales, we find that the "subdiffusive" regime is only a transient effect, MSD∝τAffiliation
HIPS, Helmholtz-Institut für pharmazeutische Forschung Saarland, Universitätscampus 8.1, 66123 Saarbrücken, Germany.PubMed ID
28076809Type
ArticleLanguage
enISSN
1542-0086ae974a485f413a2113503eed53cd6c53
10.1016/j.bpj.2016.11.900
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