Triazole-based cross-linkers in radical polymerization processes: tuning mechanical properties of poly(acrylamide) and poly( -dimethylacrylamide) hydrogels
dc.contributor.author | Götz, Tobias | |
dc.contributor.author | Schädel, Nicole | |
dc.contributor.author | Petri, Nadja | |
dc.contributor.author | Kirchhof, Manuel | |
dc.contributor.author | Bilitewski, Ursula | |
dc.contributor.author | Tovar, Günter E. M. | |
dc.contributor.author | Laschat, Sabine | |
dc.contributor.author | Southan, Alexander | |
dc.date.accessioned | 2018-11-01T13:21:22Z | |
dc.date.available | 2018-11-01T13:21:22Z | |
dc.identifier.issn | 2046-2069 | |
dc.identifier.doi | 10.1039/C8RA07145D | |
dc.identifier.uri | http://hdl.handle.net/10033/621528 | |
dc.description.abstract | Triazole-based cross-linkers with different spacer lengths and different functional end groups (acrylamides, methacrylamides, maleimides and vinylsulfonamides) were synthesized, investigated for cytotoxic and antibacterial activity, and incorporated into poly(acrylamide) (PAAm) and poly(N,N-dimethylacrylamide) (PDMAAm) hydrogels by free-radical polymerization. Hydrogels prepared with different cross-linkers and cross-linker contents between 0.2% and 1.0% were compared by gel yields, equilibrium degrees of swelling (S) and storage moduli (G0). Generally with increasing cross-linker content, G0 values of the hydrogels increased, while S values decreased. The different polymerizable cross-linker end groups resulted in a decrease of G0 in the following order for cross-linkers with C4 spacers: acrylamide > maleimide > methacrylamide > vinylsulfonamide. Longer cross-linker alkyl spacer lengths caused an increase in G0 and a decrease in S. Independent of the cross-linker used, a universal correlation between G0 and equilibrium polymer volume fraction f was found. For PAAm hydrogels, G0 ranged between 4 kPa and 23 kPa and f between 0.07 and 0.14. For PDMAAm hydrogels, G0 ranged between 0.1 kPa and 4.9 kPa and f between 0.02 and 0.06. The collected data were used to establish an empirical model to predict G0 depending on f. G0 of PAAm and PDMAAm hydrogels is given by G0 ¼ 4034 kPa f2.66 and G0 ¼ 4297 kPa f2.46, respectively. | en_US |
dc.relation.url | http://xlink.rsc.org/?DOI=C8RA07145D | en_US |
dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
dc.title | Triazole-based cross-linkers in radical polymerization processes: tuning mechanical properties of poly(acrylamide) and poly( -dimethylacrylamide) hydrogels | en_US |
dc.type | Article | en_US |
dc.contributor.department | HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany. | en_US |
dc.source.volume | 8 | |
dc.source.issue | 60 | |
dc.source.beginpage | 34743 | |
dc.source.endpage | 34753 | |
refterms.dateFOA | 2018-11-01T13:21:22Z | |
dc.source.journaltitle | RSC Advances |