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dc.contributor.authorCaputo, Mahrrouz
dc.contributor.authorHorn, Johannes
dc.contributor.authorKarch, André
dc.contributor.authorAkmatov, Manas K
dc.contributor.authorBecher, Heiko
dc.contributor.authorBraun, Bettina
dc.contributor.authorBrenner, Hermann
dc.contributor.authorCastell, Stefanie
dc.contributor.authorFischer, Beate
dc.contributor.authorGiani, Guido
dc.contributor.authorGünther, Kathrin
dc.contributor.authorHoffmann, Barbara
dc.contributor.authorJöckel, Karl-Heinz
dc.contributor.authorKeil, Thomas
dc.contributor.authorKlüppelholz, Birgit
dc.contributor.authorKrist, Lilian
dc.contributor.authorLeitzmann, Michael F
dc.contributor.authorLieb, Wolfgang
dc.contributor.authorLinseisen, Jakob
dc.contributor.authorMeisinger, Christa
dc.contributor.authorMoebus, Susanne
dc.contributor.authorObi, Nadia
dc.contributor.authorPischon, Tobias
dc.contributor.authorSchipf, Sabine
dc.contributor.authorSchmidt, Börge
dc.contributor.authorSievers, Claudia
dc.contributor.authorSteinbrecher, Astrid
dc.contributor.authorVölzke, Henry
dc.contributor.authorMikolajczyk, Rafael T
dc.date.accessioned2019-02-12T11:29:56Z
dc.date.available2019-02-12T11:29:56Z
dc.date.issued2019-01-30
dc.identifier.issn1471-2334
dc.identifier.pmid30700258
dc.identifier.doi10.1186/s12879-019-3691-2
dc.identifier.urihttp://hdl.handle.net/10033/621685
dc.description.abstractUntil now, herpes zoster (HZ)-related disease burden in Germany has been estimated based on health insurance data and clinical findings. However, the validity of self-reported HZ is unclear. This study investigated the validity of self-reported herpes zoster (HZ) and its complication postherpetic neuralgia (PHN) using data from the pretest studies of the German National Cohort (GNC) in comparison with estimates based on health insurance data. Data of 4751 participants aged between 20 and 69 years from two pretest studies of the GNC carried out in 2011 and 2012 were used. Based on self-reports of physician-diagnosed HZ and PHN, age- and sex-specific HZ incidence rates and PHN proportions were estimated. For comparison, estimates based on statutory health insurance data from the German population were considered. Eleven percent (95%-CI, 10.4 to 12.3, n = 539) of the participants reported at least one HZ episode in their lifetime. Our estimated age-specific HZ incidence rates were lower than previous estimates based on statutory health insurance data. The PHN proportion in participants older than 50 years was 5.9% (1.9 to 13.9%), which was in line with estimates based on health insurance data. As age- and sex-specific patterns were comparable with that in health insurance data, self-reported diagnosis of HZ seems to be a valid instrument for overall disease trends. Possible reasons for observed differences in incidence rates are recall bias in self-reported data or overestimation in health insurance data.en_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectGerman National Cohorten_US
dc.subjectHerpes zosteren_US
dc.subjectIncidenceen_US
dc.subjectPostherpetic neuralgiaen_US
dc.subjectSelf-reportsen_US
dc.subjectValidityen_US
dc.titleHerpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort.en_US
dc.typeArticleen_US
refterms.dateFOA2019-02-12T11:29:57Z
dc.source.journaltitleBMC infectious diseases


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