Show simple item record

dc.contributor.authorMedina, Eva
dc.contributor.authorHartl, Dominik
dc.date.accessioned2019-07-17T10:36:50Z
dc.date.available2019-07-17T10:36:50Z
dc.date.issued2018-01-01
dc.identifier.citationJ Innate Immun. 2018;10(5-6):407-413. doi: 10.1159/000489830. Epub 2018 Jun 26.en_US
dc.identifier.issn1662-8128
dc.identifier.pmid29945134
dc.identifier.doi10.1159/000489830
dc.identifier.urihttp://hdl.handle.net/10033/621881
dc.description.abstractAfter initial infection, the immune response that serves to restrict the invading pathogen needs to be tightly calibrated in order to avoid collateral immunopathological damage. This calibration is performed by specialized suppressor mechanisms, which are capable of dampening overwhelming or unremitting inflammation in order to prevent tissue damage. Myeloid-derived suppressor cells (MDSC) are emerging as key players in counter-balancing inflammatory responses and pathogenesis during infection. However, some pathogens are able to exploit the suppressive activities of MDSC to favor pathogen persistence and chronic infections. In this article, we review the current knowledge about the importance of MDSC in the context of bacterial, virus, parasites, and fungal infections.en_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectEo-myeloid-derived suppressor cellsen_US
dc.subjectInfectionsen_US
dc.subjectMonocytic-myeloid-derived suppressor cellsen_US
dc.subjectMyeloid-derived suppressor cellsen_US
dc.subjectPMN-myeloid-derived suppressor cellsen_US
dc.titleMyeloid-Derived Suppressor Cells in Infection: A General Overview.en_US
dc.typeArticleen_US
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalJournal of Innate Immunityen_US
refterms.dateFOA2019-07-17T10:36:51Z
dc.source.journaltitleJournal of innate immunity


Files in this item

Thumbnail
Name:
Medina and Hartl.pdf
Size:
76.88Kb
Format:
PDF
Description:
allowed publisher's PDF

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-ShareAlike 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International