N-WASP Guides Cancer Cells toward LPA.

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Authors
Rottner, Klemens cc
Schaks, Matthias
Issue Date
2019-11-18

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Abstract
The actin remodeling factor N-WASP is best known as an Arp2/3 complex activator in processes like endocytosis, extracellular matrix degradation, and host-pathogen interaction. In this issue of Developmental Cell, Juin et al. establish a novel trafficking function for N-WASP in driving lysophosphatidic acid-dependent chemotaxis and metastasis of pancreatic cancer cells.
Citation
Dev Cell. 2019 Nov 18;51(4):415-417. doi: 10.1016/j.devcel.2019.10.029
Affiliation
HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.
Publisher
Elsevier
Journal
Developmental Cell
URI
http://hdl.handle.net/10033/622040
DOI
10.1016/j.devcel.2019.10.029
PubMed ID
31743660
Type
Article
Language
en
ISSN
1878-1551
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