The NF-κB transcription factor c-Rel controls host defense against Citrobacter rodentium.
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Authors
Luu, MaikRomero, Rossana
Bazant, Jasmin
Abass, Elfadil
Hartmann, Sabrina
Leister, Hanna
Fischer, Florence
Mahdavi, Rouzbeh
Plaza-Sirvent, Carlos
Schmitz, Ingo
Steinhoff, Ulrich
Visekruna, Alexander

Issue Date
2019-11-14
Metadata
Show full item recordAbstract
Mice lacking CD4+ T cells or B cells are highly susceptible to Citrobacter rodentium infection. In this study, we show that the activity of the transcription factor c-Rel in lymphocytes is crucial for clearance of C. rodentium. Mice deficient for c-Rel fail to generate protective antibodies and to eradicate the pathogen.Citation
Eur J Immunol. 2019 Nov 14. doi: 10.1002/eji.201948314.Affiliation
HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.Publisher
Wiley-VCHJournal
European Journal of ImmunologyPubMed ID
31724737Type
OtherLanguage
enDescription
LetterISSN
1521-4141ae974a485f413a2113503eed53cd6c53
10.1002/eji.201948314
Scopus Count
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International
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