Antifungal Sesquiterpenoids, Rhodocoranes, from Submerged Cultures of the Wrinkled Peach Mushroom, Rhodotus palmatus.

Sandargo, Birthe; Michehl, Maira; Stadler, Marc; Surup, Frank

dc.contributor.author	Sandargo, Birthe
dc.contributor.author	Michehl, Maira
dc.contributor.author	Stadler, Marc
dc.contributor.author	Surup, Frank
dc.date.accessioned	2020-01-30T10:02:22Z
dc.date.available	2020-01-30T10:02:22Z
dc.date.issued	2019-12-10
dc.identifier.citation	J Nat Prod. 2019 Dec 10. doi: 10.1021/acs.jnatprod.9b00871	en_US
dc.identifier.issn	1520-6025
dc.identifier.pmid	31820970
dc.identifier.doi	10.1021/acs.jnatprod.9b00871
dc.identifier.uri	http://hdl.handle.net/10033/622108
dc.description.abstract	Seven previously unknown sesquiterpenoids and norsesquiterpenoids, rhodocoranes F-L (1-7), were isolated from the fermentation broth of the basidiomycete Rhodotus palmatus. Their structures were elucidated utilizing 1D and 2D NMR techniques as well as HRESIMS; they are unusual noracorane, spiro[4.4]nonene, and acorane-type sesquiterpenoids. They include the first naturally occurring cyclopentylidenefuranones (3-5) and the new tricyclic scaffold of 7. Metabolites 1-7 exhibited a general mild antimycotic activity, while 1-3 also displayed cytotoxic effects.	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier	en_US
dc.rights	Attribution-NonCommercial-ShareAlike 4.0 International	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/	*
dc.title	Antifungal Sesquiterpenoids, Rhodocoranes, from Submerged Cultures of the Wrinkled Peach Mushroom, Rhodotus palmatus.	en_US
dc.type	Article	en_US
dc.contributor.department	HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.	en_US
dc.identifier.journal	Journal of natural Products	en_US
dc.source.journaltitle	Journal of natural products