[Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].
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Authors
Jaeschke, LinaSteinbrecher, Astrid
Greiser, Karin Halina
Dörr, Marcus
Buck, Thomas
Linseisen, Jakob
Meisinger, Christa
Ahrens, Wolfgang
Becher, Heiko
Berger, Klaus
Braun, Bettina
Brenner, Hermann
Castell, Stefanie
Fischer, Beate
Franzke, Claus-Werner
Gastell, Sylvia
Günther, Kathrin
Hoffmann, Wolfgang
Holleczek, Bernd
Jagodzinski, Annika
Kaaks, Rudolf
Kluttig, Alexander
Krause, Gérard
Krist, Lilian
Kuß, Oliver
Lehnich, Anna-Therese
Leitzmann, Michael
Lieb, Wolfgang
Löffler, Markus
Michels, Karin B
Mikolajczyk, Rafael
Peters, Annette
Schikowski, Tamara
Schipf, Sabine
Schmidt, Börge
Schulze, Matthias
Völzke, Henry
Willich, Stefan N
Pischon, Tobias
Issue Date
2020-03-10
Metadata
Show full item recordAbstract
BACKGROUND: Asthma is one of the most common chronic diseases in both children and adults. Asthma first occurring in adulthood (adult-onset asthma, AOA) is associated with poorer prognosis compared to childhood-onset asthma (COA), which urgently calls for more research in this area. The aim of this work was to analyze the data on asthma collected in the German National Cohort and compare it with the German Health Interview and Examination Survey for Adults (DEGS), in particular regarding AOA. MATERIAL AND METHODS: Our analysis was based on the dataset of the main questionnaire at mid-term of the German National Cohort baseline examination, comprising 101,723 participants. Variables considered in the analyses were self-reported diagnosis of asthma, age at first diagnosis, asthma treatment in the past 12 months, age, and sex. RESULTS: In the midterm dataset, 8.7% of women and 7.0% of men in the German National Cohort reported that they had ever been diagnosed with asthma. Approximately one third of participants with asthma received their initial diagnosis before their 18th birthday. COA affected 2.2% of women and 2.8% of men, whereas AOA affected 6.5% of women and 4.2% of men. During the previous 12 months, 33% of COA cases and 60% of AOA cases were medically treated. CONCLUSION: The proportion of persons affected by asthma in the German National Cohort, as well as observed patterns regarding age and gender, corresponds to other data sources such as DEGS. However, in our analysis, the proportion of individuals with AOA was higher than described in the literature. The increase in cumulative asthma diagnoses with age is markedly steeper in younger participants, indicating a rising trend over time.Citation
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Mar 3. pii: 10.1007/s00103-020-03105-y. doi: 10.1007/s00103-020-03105-y.Affiliation
HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.Publisher
SpringerPubMed ID
32157352Type
ArticleOther
Language
deEISSN
1437-1588ae974a485f413a2113503eed53cd6c53
10.1007/s00103-020-03108-9
Scopus Count
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- Creative Commons
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