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dc.contributor.authorJaeschke, Lina
dc.contributor.authorSteinbrecher, Astrid
dc.contributor.authorGreiser, Karin Halina
dc.contributor.authorDörr, Marcus
dc.contributor.authorBuck, Thomas
dc.contributor.authorLinseisen, Jakob
dc.contributor.authorMeisinger, Christa
dc.contributor.authorAhrens, Wolfgang
dc.contributor.authorBecher, Heiko
dc.contributor.authorBerger, Klaus
dc.contributor.authorBraun, Bettina
dc.contributor.authorBrenner, Hermann
dc.contributor.authorCastell, Stefanie
dc.contributor.authorFischer, Beate
dc.contributor.authorFranzke, Claus-Werner
dc.contributor.authorGastell, Sylvia
dc.contributor.authorGünther, Kathrin
dc.contributor.authorHoffmann, Wolfgang
dc.contributor.authorHolleczek, Bernd
dc.contributor.authorJagodzinski, Annika
dc.contributor.authorKaaks, Rudolf
dc.contributor.authorKluttig, Alexander
dc.contributor.authorKrause, Gérard
dc.contributor.authorKrist, Lilian
dc.contributor.authorKuß, Oliver
dc.contributor.authorLehnich, Anna-Therese
dc.contributor.authorLeitzmann, Michael
dc.contributor.authorLieb, Wolfgang
dc.contributor.authorLöffler, Markus
dc.contributor.authorMichels, Karin B
dc.contributor.authorMikolajczyk, Rafael
dc.contributor.authorPeters, Annette
dc.contributor.authorSchikowski, Tamara
dc.contributor.authorSchipf, Sabine
dc.contributor.authorSchmidt, Börge
dc.contributor.authorSchulze, Matthias
dc.contributor.authorVölzke, Henry
dc.contributor.authorWillich, Stefan N
dc.contributor.authorPischon, Tobias
dc.date.accessioned2020-03-20T15:01:30Z
dc.date.available2020-03-20T15:01:30Z
dc.date.issued2020-03-10
dc.identifier.citationBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Mar 3. pii: 10.1007/s00103-020-03105-y. doi: 10.1007/s00103-020-03105-y.en_US
dc.identifier.pmid32157352
dc.identifier.doi10.1007/s00103-020-03108-9
dc.identifier.urihttp://hdl.handle.net/10033/622215
dc.description.abstractBACKGROUND: Asthma is one of the most common chronic diseases in both children and adults. Asthma first occurring in adulthood (adult-onset asthma, AOA) is associated with poorer prognosis compared to childhood-onset asthma (COA), which urgently calls for more research in this area. The aim of this work was to analyze the data on asthma collected in the German National Cohort and compare it with the German Health Interview and Examination Survey for Adults (DEGS), in particular regarding AOA. MATERIAL AND METHODS: Our analysis was based on the dataset of the main questionnaire at mid-term of the German National Cohort baseline examination, comprising 101,723 participants. Variables considered in the analyses were self-reported diagnosis of asthma, age at first diagnosis, asthma treatment in the past 12 months, age, and sex. RESULTS: In the midterm dataset, 8.7% of women and 7.0% of men in the German National Cohort reported that they had ever been diagnosed with asthma. Approximately one third of participants with asthma received their initial diagnosis before their 18th birthday. COA affected 2.2% of women and 2.8% of men, whereas AOA affected 6.5% of women and 4.2% of men. During the previous 12 months, 33% of COA cases and 60% of AOA cases were medically treated. CONCLUSION: The proportion of persons affected by asthma in the German National Cohort, as well as observed patterns regarding age and gender, corresponds to other data sources such as DEGS. However, in our analysis, the proportion of individuals with AOA was higher than described in the literature. The increase in cumulative asthma diagnoses with age is markedly steeper in younger participants, indicating a rising trend over time.en_US
dc.language.isodeen_US
dc.publisherSpringeren_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectCohorten_US
dc.subjectCross-sectional studyen_US
dc.subjectEpidemiologyen_US
dc.subjectGermanyen_US
dc.subjectObservational studyen_US
dc.title[Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn1437-1588
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalBundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutzen_US
refterms.dateFOA2020-03-20T15:01:31Z
dc.source.journaltitleBundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
dc.source.countryGermany


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