A Single-Center Prospective Cohort Study on Postsplenectomy Sepsis and its Prevention.
dc.contributor.author | Rieg, Siegbert | |
dc.contributor.author | Bechet, Lena | |
dc.contributor.author | Naujoks, Kai | |
dc.contributor.author | Hromek, Julia | |
dc.contributor.author | Lange, Berit | |
dc.contributor.author | Juzek-Küpper, Marc-Fabian | |
dc.contributor.author | Stete, Katarina | |
dc.contributor.author | Müller, Matthias C | |
dc.contributor.author | Jost, Insa | |
dc.contributor.author | Kern, Winfried V | |
dc.contributor.author | Theilacker, Christian | |
dc.date.accessioned | 2020-07-29T09:59:10Z | |
dc.date.available | 2020-07-29T09:59:10Z | |
dc.date.issued | 2020-02-13 | |
dc.identifier.citation | Open Forum Infect Dis. 2020;7(3):ofaa050. Published 2020 Feb 13. doi:10.1093/ofid/ofaa050. | en_US |
dc.identifier.issn | 2328-8957 | |
dc.identifier.pmid | 32158777 | |
dc.identifier.doi | 10.1093/ofid/ofaa050 | |
dc.identifier.uri | http://hdl.handle.net/10033/622370 | |
dc.description.abstract | A total of 459 asplenic patients were enrolled, and 426 patients were followed prospectively over a median period of 2.9 years. Pneumococcal vaccine uptake within 3 months of splenectomy or first diagnosis of asplenia was 27% vs 71% among delayed study entry and early study entry patients, respectively (P < .001). Forty-four episodes of severe sepsis or septic shock occurred in study patients: 22 after study entry and 22 before study entry. Streptococcus pneumoniae was more frequent among sepsis episodes that occurred before study entry (8/22) than after study entry (1/22 episodes). For episodes occurring after study entry, only a higher Charlson comorbidity index score was significantly associated with severe sepsis/septic shock postsplenectomy. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Oxford University Press | en_US |
dc.rights | Attribution-NonCommercial-ShareAlike 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | * |
dc.subject | asplenia | en_US |
dc.subject | postsplenectomy sepsis | en_US |
dc.subject | vaccination | en_US |
dc.title | A Single-Center Prospective Cohort Study on Postsplenectomy Sepsis and its Prevention. | en_US |
dc.type | Article | en_US |
dc.identifier.journal | Open forum infectious diseases | en_US |
dc.source.volume | 7 | |
dc.source.issue | 3 | |
dc.source.beginpage | ofaa050 | |
dc.source.endpage | ||
refterms.dateFOA | 2020-07-29T09:59:10Z | |
dc.source.journaltitle | Open forum infectious diseases | |
dc.source.country | United States |