LifeTime and improving European healthcare through cell-based interceptive medicine.
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Gorski, Stanislaw A
Bertero, Michela G
Bredenoord, Annelien L
De Strooper, Bart
Fernández, Xosé M
Gasser, Susan M
Knoblich, Jürgen A
Marti-Renom, Marc A
Netea, Mihai G
Novak, Halina R
Schultze, Joachim L
Theis, Fabian J
van Oudenaarden, Alexander
MetadataShow full item record
AbstractLifeTime aims to track, understand and target human cells during the onset and progression of complex diseases and their response to therapy at single-cell resolution. This mission will be implemented through the development and integration of single-cell multi-omics and imaging, artificial intelligence and patient-derived experimental disease models during progression from health to disease. Analysis of such large molecular and clinical datasets will discover molecular mechanisms, create predictive computational models of disease progression, and reveal new drug targets and therapies. Timely detection and interception of disease embedded in an ethical and patient-centered vision will be achieved through interactions across academia, hospitals, patient-associations, health data management systems and industry. Applying this strategy to key medical challenges in cancer, neurological, infectious, chronic inflammatory and cardiovascular diseases at the single-cell level will usher in cell-based interceptive medicine in Europe over the next decade.
CitationNature. 2020 Sep 7. doi: 10.1038/s41586-020-2715-9. Epub ahead of print.
AffiliationTWINCORE, Zentrum für experimentelle und klinische Infektionsforschung GmbH,Feodor-Lynen Str. 7, 30625 Hannover, Germany.
PublisherNature publishing group(NPG)
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International
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