Total Synthesis and Structure Revision of Halioxepine.

Poock, Caroline; Kalesse, Markus

dc.contributor.author	Poock, Caroline
dc.contributor.author	Kalesse, Markus
dc.date.accessioned	2021-01-12T13:02:50Z
dc.date.available	2021-01-12T13:02:50Z
dc.date.issued	2020-11-20
dc.identifier.citation	Chemistry. 2020 Nov 20. doi: 10.1002/chem.202004847.	en_US
dc.identifier.pmid	33215739
dc.identifier.doi	10.1002/chem.202004847
dc.identifier.uri	http://hdl.handle.net/10033/622672
dc.description.abstract	The first total synthesis of halioxepine is accomplished using a 1,4-addition for constructing the quaternary center at C10 and a halo etherification for the generation of the tertiary ether at C7. The correct structure of halioxepine was determined by assembling different enantiomeric building blocks and by changing the relative configuration between C10 and C15.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.rights	Attribution 4.0 International	*
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	*
dc.subject	halo etherification	en_US
dc.subject	natural product synthesis	en_US
dc.subject	quaternary stereocenter	en_US
dc.subject	structure elucidation	en_US
dc.subject	terpenoids	en_US
dc.title	Total Synthesis and Structure Revision of Halioxepine.	en_US
dc.type	Article	en_US
dc.identifier.eissn	1521-3765
dc.contributor.department	HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.	en_US
dc.identifier.journal	Chemistry (Weinheim an der Bergstrasse, Germany)	en_US
refterms.dateFOA	2021-01-12T13:02:50Z
dc.source.journaltitle	Chemistry (Weinheim an der Bergstrasse, Germany)
dc.source.country	Germany