A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Hitch, Thomas C A
Lesker, Till R
Hernández, Sara B
Buhl, Eva M
M D'Agostino, Paul
Parreira, Valeria R
Doden, Heidi L
Alves, João M P
Suarez, Laura Navarro
Neumann, Anthony P
de Wouters, Tomas
Taverne-Thiele, Anja J
Wells, Jerry M
Ridlon, Jason M
Gulder, Tobias A M
MetadataShow full item record
AbstractOur knowledge about the gut microbiota of pigs is still scarce, despite the importance of these animals for biomedical research and agriculture. Here, we present a collection of cultured bacteria from the pig gut, including 110 species across 40 families and nine phyla. We provide taxonomic descriptions for 22 novel species and 16 genera. Meta-analysis of 16S rRNA amplicon sequence data and metagenome-assembled genomes reveal prevalent and pig-specific species within Lactobacillus, Streptococcus, Clostridium, Desulfovibrio, Enterococcus, Fusobacterium, and several new genera described in this study. Potentially interesting functions discovered in these organisms include a fucosyltransferase encoded in the genome of the novel species Clostridium porci, and prevalent gene clusters for biosynthesis of sactipeptide-like peptides. Many strains deconjugate primary bile acids in in vitro assays, and a Clostridium scindens strain produces secondary bile acids via dehydroxylation. In addition, cells of the novel species Bullifex porci are coccoidal or spherical under the culture conditions tested, in contrast with the usual helical shape of other members of the family Spirochaetaceae. The strain collection, called ‘Pig intestinal bacterial collection’ (PiBAC), is publicly available at www.dsmz.de/pibac and opens new avenues for functional studies of the pig gut microbiota.
CitationNat Commun. 2020 Dec 15;11(1):6389. doi: 10.1038/s41467-020-19929-w.
AffiliationHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.
PublisherNature Pulishing Group
The following license files are associated with this item:
- Creative Commons
- Core gut microbiota in Jinhua pigs and its correlation with strain, farm and weaning age.
- Authors: Yang H, Xiao Y, Wang J, Xiang Y, Gong Y, Wen X, Li D
- Issue date: 2018 May
- The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.
- Authors: Lagkouvardos I, Pukall R, Abt B, Foesel BU, Meier-Kolthoff JP, Kumar N, Bresciani A, Martínez I, Just S, Ziegler C, Brugiroux S, Garzetti D, Wenning M, Bui TP, Wang J, Hugenholtz F, Plugge CM, Peterson DA, Hornef MW, Baines JF, Smidt H, Walter J, Kristiansen K, Nielsen HB, Haller D, Overmann J, Stecher B, Clavel T
- Issue date: 2016 Aug 8
- Taxonomic annotation of 16S rRNA sequences of pig intestinal samples using MG-RAST and QIIME2 generated different microbiota compositions.
- Authors: Lima J, Manning T, Rutherford KM, Baima ET, Dewhurst RJ, Walsh P, Roehe R
- Issue date: 2021 Jul
- A Bacterial Genome and Culture Collection of Gut Microbial in Weanling Piglet.
- Authors: Dong B, Lin X, Jing X, Hu T, Zhou J, Chen J, Xiao L, Wang B, Chen Z, Liu J, Hu Y, Liu G, Liu S, Liu J, Wei W, Zou Y
- Issue date: 2022 Feb 23
- Composition and functional diversity of fecal bacterial community of wild boar, commercial pig and domestic native pig as revealed by 16S rRNA gene sequencing.
- Authors: Huang J, Zhang W, Fan R, Liu Z, Huang T, Li J, Du T, Xiong T
- Issue date: 2020 May