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dc.contributor.authorChuankid, Boontiya
dc.contributor.authorSchrey, Hedda
dc.contributor.authorThongbai, Benjarong
dc.contributor.authorRaspé, Olivier
dc.contributor.authorArnold, Norbert
dc.contributor.authorHyde, Kevin David
dc.contributor.authorStadler, Marc
dc.date.accessioned2021-04-27T14:38:05Z
dc.date.available2021-04-27T14:38:05Z
dc.date.issued2020-12-01
dc.identifier.citationd. Mycol Progress 19, 1525–1536 (2020). https://doi.org/10.1007/s11557-020-01643-y.en_US
dc.identifier.issn1617416X
dc.identifier.doi10.1007/s11557-020-01643-y
dc.identifier.urihttp://hdl.handle.net/10033/622848
dc.description.abstractSubmerged cultures of the edible mushrooms Phlebopus portentosus and Phlebopus spongiosus were screened for their secondary metabolites by HPLC-UV/Vis and HR-LC-ESI-MS. Two new compounds, 9′-hydroxyphenyl pulvinone (1), containing an unusual pulvinone structure, and phlebopyron (2), together with the seven known pigments, atromentic acid (3), xerocomic acid (4), variegatic acid (5), methyl atromentate (6), methyl isoxerocomate (7), methyl variegatate (8), and variegatorubin (9) were isolated from the cultures. Their structures were assigned on the basis of extensive 1D/2D NMR spectroscopic analyses, as well as HR-ESI-MS, and HR-ESI-MS/MS measurements. Furthermore, the isolated compounds were evaluated for their antimicrobial and cytotoxic properties. 9′-hydroxyphenyl pulvinone (1), xerocomic acid (4), and methyl variegatate (8) exhibited weak to moderate cytotoxic activities against several tumor cell lines. The present paper provides a comprehensive characterization of pigments from the class of pulvinic acids that are present in the basidiomes of many edible bolete species.en_US
dc.description.sponsorshipThailand Research Funden_US
dc.language.isoenen_US
dc.publisherSpringer.comen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectBasidiomycotaen_US
dc.subjectBoletalesen_US
dc.subjectEdible mushroomsen_US
dc.subjectPulvinic acid derivativesen_US
dc.subjectSecondary metabolitesen_US
dc.subjectStructure elucidationen_US
dc.titleSecondary metabolites of Phlebopus species from Northern Thailanden_US
dc.typeArticleen_US
dc.identifier.eissn18618952
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalMycological Progressen_US
dc.identifier.eid2-s2.0-85097148221
dc.identifier.scopusidSCOPUS_ID:85097148221
dc.source.volume19
dc.source.issue12
dc.source.beginpage1525
dc.source.endpage1536
refterms.dateFOA2021-04-27T14:38:06Z
dc.source.journaltitleMycological Progress


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Except where otherwise noted, this item's license is described as Attribution 4.0 International