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dc.contributor.authorSingh, Kumar Siddharth
dc.contributor.authorAnand, Santosh
dc.contributor.authorDholpuria, Sunny
dc.contributor.authorSharma, Jitendra Kumar
dc.contributor.authorBlankenfeldt, Wulf
dc.contributor.authorShouche, Yogesh
dc.date.accessioned2021-05-17T08:59:53Z
dc.date.available2021-05-17T08:59:53Z
dc.date.issued2021-04-15
dc.identifier.citationEnviron Chem Lett (2021). https://doi.org/10.1007/s10311-021-01238-3.en_US
dc.identifier.issn1610-3653
dc.identifier.doi10.1007/s10311-021-01238-3
dc.identifier.urihttp://hdl.handle.net/10033/622871
dc.description.abstractAntimicrobial resistance is a global threat that kills at least 75,000 people every year worldwide and causes extended hospital stays. In the coming 10 years, antimicrobial resistance is projected to have huge health and economic burden on countries, and the scarcity of available antibiotics further worsens the situation. Antimicrobial resistance results mainly from indiscriminate antibiotic usage in humans, animals and agriculture, and from the rapid emergence and dissemination of resistant pathogens. This issue is challenging for antibiotic stewardship, strict regulations on antibiotics usage, large-scale surveillance and responsible public behavior. This demands international cooperation and integrated efforts under the ‘one-health’ strategy. Here, we review antimicrobial resistance and the one-health strategy. We discuss the historical issue of using antibiotics. We highlight the effectiveness of hygiene in livestock rearing, careful antibiotic usage and large-scale surveillance of animals, humans and environment domains. We present strategies for mitigation of antimicrobial resistance, exemplified by the successful ban of triclosan which induced a significant decline of resistant pathogens. We emphasize the benefits of the global antibiotic resistance partnership and of the one-health participation of stakeholders from public, healthcare professionals and government to mitigate antimicrobial resistance.en_US
dc.language.isoenen_US
dc.publisherSpringer Science and Business Media LLCen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://www.springer.com/tdm
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectEnvironmental Chemistryen_US
dc.titleAntimicrobial resistance dynamics and the one-health strategy: a reviewen_US
dc.typeReviewen_US
dc.identifier.eissn1610-3661
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalEnvironmental Chemistry Lettersen_US
dc.identifier.pii1238
dc.source.journaltitleEnvironmental Chemistry Letters


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