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dc.contributor.authorLücke, Daniel
dc.contributor.authorKalesse, Markus
dc.date.accessioned2021-05-18T09:39:40Z
dc.date.available2021-05-18T09:39:40Z
dc.date.issued2021-04-09
dc.identifier.citationChemistry. 2021 Apr 26;27(24):7085-7089. doi: 10.1002/chem.202100553. Epub 2021 Apr 9.en_US
dc.identifier.pmid33769622
dc.identifier.doi10.1002/chem.202100553
dc.identifier.urihttp://hdl.handle.net/10033/622876
dc.description.abstractThe synthesis of desepoxy-tedanolide C was accomplished and provided experimental evidence on the configuration of tedanolide C. The reported chemical shifts and coupling constants point to a configuration different from the published structure and analogous to the structures of the other members of this family of natural products. The key step is a Kiyooka aldol protocol for the stereoselective synthesis of the tertiary alcohol flanked by three additional oxygenated carbon atoms. Furthermore, two additional aldol reactions and a Julia-Kocienski olefination were used to assemble the carbon framework.en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectKiyooka aldolen_US
dc.subjectpolyketidesen_US
dc.subjectstructure elucidationen_US
dc.subjecttedanolie Cen_US
dc.subjecttertiary alcoholen_US
dc.titleSynthesis of Desepoxy-Tedanolide C.en_US
dc.typeArticleen_US
dc.identifier.eissn1521-3765
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalChemistry (Weinheim an der Bergstrasse, Germany)en_US
dc.source.volume27
dc.source.issue24
dc.source.beginpage7085
dc.source.endpage7089
refterms.dateFOA2021-05-18T09:39:41Z
dc.source.journaltitleChemistry (Weinheim an der Bergstrasse, Germany)
dc.source.countryGermany


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International