Analogs of the carotane antibiotic fulvoferruginin from submerged cultures of a Thai sp.
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Authors
Sandargo, BirtheKaysan, Leon
Teponno, Rémy B
Richter, Christian
Thongbai, Benjarong
Surup, Frank
Stadler, Marc
Issue Date
2021-06-04
Metadata
Show full item recordAbstract
A recent find of a Marasmius species in Northern Thailand led to the isolation of five unprecedented derivatives of the carotane antibiotic fulvoferruginin (1), fulvoferruginins B-F (2-6). The structures of these sesquiterpenoids were elucidated using HRESIMS, 1D and 2D NMR, as well as CD spectroscopy. Assessing the bioactivity, fulvoferruginin emerged as a potent cytotoxic agent of potential pharmaceutical interest.Citation
Beilstein J Org Chem. 2021 Jun 4;17:1385-1391. doi: 10.3762/bjoc.17.97.Affiliation
HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.Publisher
Beilstein InstitutPubMed ID
34136017Type
ArticleLanguage
enISSN
1860-5397ae974a485f413a2113503eed53cd6c53
10.3762/bjoc.17.97
Scopus Count
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- Creative Commons