Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2.
dc.contributor.author | Cheng, Bichu | |
dc.contributor.author | Müller, Rolf | |
dc.contributor.author | Trauner, Dirk | |
dc.date.accessioned | 2021-08-12T11:49:40Z | |
dc.date.available | 2021-08-12T11:49:40Z | |
dc.date.issued | 2017-08-30 | |
dc.identifier.citation | Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12755-12759. doi: 10.1002/anie.201705387. Epub 2017 Aug 30. | en_US |
dc.identifier.pmid | 28731542 | |
dc.identifier.doi | 10.1002/anie.201705387 | |
dc.identifier.uri | http://hdl.handle.net/10033/622985 | |
dc.description.abstract | The cystobactamids are a family of antibacterial natural products with unprecedented chemical scaffolds that are active against both Gram-positive and Gram-negative pathogens. Herein, we describe the first total synthesis of cystobactamid 919-2 from three fragments. Our convergent synthesis enabled both the confirmation of the correct structure and the determination of the absolute configuration of cystobactamid 919-2. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wiley-VCH | en_US |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | absolute configuration | en_US |
dc.subject | antibiotics | en_US |
dc.subject | peptides | en_US |
dc.subject | structure elucidation | en_US |
dc.subject | total synthesis | en_US |
dc.title | Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2. | en_US |
dc.type | Article | en_US |
dc.identifier.eissn | 1521-3773 | |
dc.contributor.department | HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany. | en_US |
dc.identifier.journal | Angewandte Chemie (International ed. in English) | en_US |
dc.source.volume | 56 | |
dc.source.issue | 41 | |
dc.source.beginpage | 12755 | |
dc.source.endpage | 12759 | |
refterms.dateFOA | 2021-08-12T11:49:41Z | |
dc.source.journaltitle | Angewandte Chemie (International ed. in English) | |
dc.source.country | Germany |