Recent Applications of the Diels-Alder Reaction in the Synthesis of Natural Products (2017-2020)
dc.contributor.author | Sara, Alexandru A. | |
dc.contributor.author | Um-E-Farwa, Um E.Farwa | |
dc.contributor.author | Saeed, Aamer | |
dc.contributor.author | Kalesse, Markus | |
dc.date.accessioned | 2021-09-30T10:07:26Z | |
dc.date.available | 2021-09-30T10:07:26Z | |
dc.date.issued | 2021-06-21 | |
dc.identifier.citation | (2021) Synthesis (Germany), doi:10.1055/a-1532-4763. | en_US |
dc.identifier.issn | 00397881 | |
dc.identifier.doi | 10.1055/a-1532-4763 | |
dc.identifier.uri | http://hdl.handle.net/10033/623053 | |
dc.description.abstract | The Diels-Alder reaction has long been established as an extremely useful procedure in the toolbox of natural product chemists. It tolerates a wide spectrum of building blocks of different complexity and degrees of derivatization, and enables the formation of six-membered rings with well-defined stereochemistry. In recent years, many total syntheses of natural products have been reported that rely, at some point, on the use of a [4+2]-cycloaddition step. Among classic approaches, several modifications of the Diels-Alder reaction, such as hetero-Diels-Alder reactions, dehydro-Diels-Alder reactions and domino-Diels-Alder reactions, have been employed to extend the scope of this process in the synthesis of natural products. Our short review covers applications of the Diels-Alder reaction in natural product syntheses between 2017 and 2020, as well as selected methodologies which are inspired by, or that can be used to access natural products. 1 Introduction 2 Syntheses from 2017 3 Syntheses from 2018 4 Syntheses from 2019 5 Syntheses from 2020 6 Conclusion. © 2021 Georg Thieme Verlag. All rights reserved | en_US |
dc.publisher | Thieme | en_US |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | cycloaddition | en_US |
dc.subject | Diels-Alder reaction | en_US |
dc.subject | natural products | en_US |
dc.subject | recent advances | en_US |
dc.subject | stereocontrol | en_US |
dc.subject | total synthesis | en_US |
dc.title | Recent Applications of the Diels-Alder Reaction in the Synthesis of Natural Products (2017-2020) | en_US |
dc.type | Review | en_US |
dc.identifier.eissn | 1437210X | |
dc.contributor.department | HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany. | en_US |
dc.identifier.journal | Synthesis (Germany) | en_US |
dc.identifier.eid | 2-s2.0-85112214577 | |
dc.identifier.scopusid | SCOPUS_ID:85112214577 | |
dc.source.journaltitle | Synthesis (Germany) |