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dc.contributor.authorSara, Alexandru A.
dc.contributor.authorUm-E-Farwa, Um E.Farwa
dc.contributor.authorSaeed, Aamer
dc.contributor.authorKalesse, Markus
dc.date.accessioned2021-09-30T10:07:26Z
dc.date.available2021-09-30T10:07:26Z
dc.date.issued2021-06-21
dc.identifier.citation(2021) Synthesis (Germany), doi:10.1055/a-1532-4763.en_US
dc.identifier.issn00397881
dc.identifier.doi10.1055/a-1532-4763
dc.identifier.urihttp://hdl.handle.net/10033/623053
dc.description.abstractThe Diels-Alder reaction has long been established as an extremely useful procedure in the toolbox of natural product chemists. It tolerates a wide spectrum of building blocks of different complexity and degrees of derivatization, and enables the formation of six-membered rings with well-defined stereochemistry. In recent years, many total syntheses of natural products have been reported that rely, at some point, on the use of a [4+2]-cycloaddition step. Among classic approaches, several modifications of the Diels-Alder reaction, such as hetero-Diels-Alder reactions, dehydro-Diels-Alder reactions and domino-Diels-Alder reactions, have been employed to extend the scope of this process in the synthesis of natural products. Our short review covers applications of the Diels-Alder reaction in natural product syntheses between 2017 and 2020, as well as selected methodologies which are inspired by, or that can be used to access natural products. 1 Introduction 2 Syntheses from 2017 3 Syntheses from 2018 4 Syntheses from 2019 5 Syntheses from 2020 6 Conclusion. © 2021 Georg Thieme Verlag. All rights reserveden_US
dc.publisherThiemeen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectcycloadditionen_US
dc.subjectDiels-Alder reactionen_US
dc.subjectnatural productsen_US
dc.subjectrecent advancesen_US
dc.subjectstereocontrolen_US
dc.subjecttotal synthesisen_US
dc.titleRecent Applications of the Diels-Alder Reaction in the Synthesis of Natural Products (2017-2020)en_US
dc.typeReviewen_US
dc.identifier.eissn1437210X
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalSynthesis (Germany)en_US
dc.identifier.eid2-s2.0-85112214577
dc.identifier.scopusidSCOPUS_ID:85112214577
dc.source.journaltitleSynthesis (Germany)


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International