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dc.contributor.authorHankel, Julia
dc.contributor.authorBodmann, Björn
dc.contributor.authorTodte, Matthias
dc.contributor.authorGalvez, Eric
dc.contributor.authorStrowig, Till
dc.contributor.authorRadko, Dimitri
dc.contributor.authorAntakli, Ali
dc.contributor.authorVisscher, Christian
dc.date.accessioned2021-10-04T11:18:46Z
dc.date.available2021-10-04T11:18:46Z
dc.date.issued2021-08-23
dc.identifier.citationPathogens. 2021 Aug 23;10(8):1068. doi: 10.3390/pathogens10081068.en_US
dc.identifier.issn2076-0817
dc.identifier.pmid34451532
dc.identifier.doi10.3390/pathogens10081068
dc.identifier.urihttp://hdl.handle.net/10033/623058
dc.description.abstractMinimizing the clinical signs of Enterococcus cecorum infections causing enterococcal spondylitis in broiler herds is successful when initiated as metaphylaxis in the first week of life. Mechanistically, either the Enterococcus species present at that time are reduced by antibiotic treatment or antibiotic treatment might induce changes in intestinal microbiota composition with an indirect and subsequent influence. The aim of the present study was to examine the cecal microbiota of chickens after administering lincospectin or different additives to evaluate whether these additives have lincospectin-like effects on microbiota. Therefore, 157,400 broiler chickens were reared in four chicken houses (~40,000 birds each) on a broiler farm with history of enterococcal spondylitis. Each flock was treated either with lincospectin or water soluble esterified butyrins, Bacillus (B.) licheniformis or palm oil was added via drinking water during the first days of life. Ten birds per house were dissected at days 11, 20 and 33 of life and cecal microbiota were analyzed (16S rRNA gene sequencing). Lincospectin treatment elicited significant changes in the cecal microbiota composition until slaughter age. Among the tested additives, effects of B. licheniformis on cecal microbiota composition were most similar to those seen after the treatment with lincospectin at day 11.en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject16S rRNA geneen_US
dc.subjectbacterial pathogensen_US
dc.subjectbeta diversityen_US
dc.subjectpoultryen_US
dc.titleComparison of Chicken Cecal Microbiota after Metaphylactic Treatment or Following Administration of Feed Additives in a Broiler Farm with Enterococcal Spondylitis History.en_US
dc.typeArticleen_US
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalPathogens (Basel, Switzerland)en_US
dc.source.volume10
dc.source.issue8
refterms.dateFOA2021-10-04T11:18:47Z
dc.source.journaltitlePathogens (Basel, Switzerland)
dc.source.countrySwitzerland


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International