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dc.contributor.authorYe, Liqing
dc.contributor.authorAmbi, Uddhav B
dc.contributor.authorOlguin-Nava, Marco
dc.contributor.authorGribling-Burrer, Anne-Sophie
dc.contributor.authorAhmad, Shazeb
dc.contributor.authorBohn, Patrick
dc.contributor.authorWeber, Melanie M
dc.contributor.authorSmyth, Redmond P
dc.date.accessioned2021-10-27T12:31:59Z
dc.date.available2021-10-27T12:31:59Z
dc.date.issued2021-09-08
dc.identifier.citationViruses. 2021 Sep 8;13(9):1788. doi: 10.3390/v13091788.en_US
dc.identifier.pmid34578369
dc.identifier.doi10.3390/v13091788
dc.identifier.urihttp://hdl.handle.net/10033/623081
dc.description.abstractTo generate infectious viral particles, viruses must specifically select their genomic RNA from milieu that contains a complex mixture of cellular or non-genomic viral RNAs. In this review, we focus on the role of viral encoded RNA structures in genome packaging. We first discuss how packaging signals are constructed from local and long-range base pairings within viral genomes, as well as inter-molecular interactions between viral and host RNAs. Then, how genome packaging is regulated by the biophysical properties of RNA. Finally, we examine the impact of RNA packaging signals on viral evolution.en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectRNAen_US
dc.subjectRNA structureen_US
dc.subjectRNA virusen_US
dc.subjectevolutionen_US
dc.subjectgenome packagingen_US
dc.subjectviral assemblyen_US
dc.titleRNA Structures and Their Role in Selective Genome Packaging.en_US
dc.typeArticleen_US
dc.identifier.eissn1999-4915
dc.contributor.departmentHIRI, Helmholtz-Institut für RNA-basierte Infektionsforschung, Josef-Shneider Strasse 2, 97080 Würzburg, Germany.en_US
dc.identifier.journalVirusesen_US
dc.source.volume13
dc.source.issue9
refterms.dateFOA2021-10-27T12:32:00Z
dc.source.journaltitleViruses
dc.source.countrySwitzerland


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International