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Issue Date
2021-11-12
Metadata
Show full item recordAbstract
In the course of screening new streptomycete strains, the strain Streptomyces sp. Cl 58-27 caught our attention due to its interesting secondary metabolite production profile. Here, we report the isolation and characterization of an ansamycin natural product that belongs structurally to the already known kendomycins. The structure of the new kendomycin E was elucidated using NMR spectroscopy, and the corresponding biosynthetic gene cluster was identified by sequencing the genome of Streptomyces sp. Cl 58-27 and conducting a detailed analysis of secondary metabolism gene clusters using bioinformatic tools.Citation
Molecules. 2021 Nov 12;26(22):6834. doi: 10.3390/molecules26226834.Affiliation
HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.Publisher
MDPIJournal
Molecules (Basel, Switzerland)PubMed ID
34833926Type
ArticleLanguage
enEISSN
1420-3049ae974a485f413a2113503eed53cd6c53
10.3390/molecules26226834
Scopus Count
The following license files are associated with this item:
- Creative Commons
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