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dc.contributor.authorHassan, Khadija
dc.contributor.authorMatio Kemkuignou, Blondelle
dc.contributor.authorStadler, Marc
dc.date.accessioned2021-12-20T12:00:51Z
dc.date.available2021-12-20T12:00:51Z
dc.date.issued2021-11-24
dc.identifier.citationMolecules. 2021 Nov 24;26(23):7090. doi: 10.3390/molecules26237090.en_US
dc.identifier.pmid34885672
dc.identifier.doi10.3390/molecules26237090
dc.identifier.urihttp://hdl.handle.net/10033/623124
dc.description.abstractIn the search for novel anti-infectives from natural sources, fungi, in particular basidiomycetes, have proven to still harbor so much potential in terms of secondary metabolites diversity. There have been numerous reports on isolating numerous secondary metabolites from genus Laetiporus. This study reports on two new triterpenoids, laetiporins C and D, and four known triterpenes from the fruiting body of L. sulphureus. The structures of the isolated compounds were elucidated based on their 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data in combination with high-resolution electrospray mass spectrometric (HR-ESIMS) data. Laetiporin C exhibited weak antifungal activity against Mucor hiemalis. Furthermore, the compounds showed weak antiproliferative activity against the mouse fibroblast L929 and human cancer cell lines, including KB-3-1, A431, MCF-7, PC-3 and A549.en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectLaetiporus sp.en_US
dc.subjectantimicrobialen_US
dc.subjectantiproliferativeen_US
dc.subjecttriterpenoidsen_US
dc.titleTwo New Triterpenes from Basidiomata of the Medicinal and Edible Mushroom laetiporus sulphureus .en_US
dc.typeArticleen_US
dc.identifier.eissn1420-3049
dc.contributor.departmentHZI, Helmholtz Zentrum für Infektionsforschung, GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.en_US
dc.identifier.journalMolecules (Basel, Switzerland)en_US
dc.source.volume26
dc.source.issue23
refterms.dateFOA2021-12-20T12:00:51Z
dc.source.journaltitleMolecules (Basel, Switzerland)
dc.source.countrySwitzerland


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International