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dc.contributor.authorApenteng, Ofosuhene O.
dc.contributor.authorKwabla, Mavis Pearl
dc.contributor.authorIsmail, Noor Azina
dc.contributor.authorGold, Kafilah Lola
dc.date.accessioned2022-01-28T10:27:27Z
dc.date.available2022-01-28T10:27:27Z
dc.date.issued2021-11-11
dc.identifier.citation(2021)Journal of HIV/AIDS \& Social Services doi:10.1080/15381501.2021.2000545.en_US
dc.identifier.issn15381501
dc.identifier.doi10.1080/15381501.2021.2000545
dc.identifier.urihttp://hdl.handle.net/10033/623155
dc.description.abstractEach year, millions of children are born with human immunodeficiency virus (HIV), a quarter of whom adhere poorly to HIV treatment guidelines. This study uses a simple mathematical model to investigate the basic dynamic processes by which infected newborns under treatment progress to AIDS and contribute to its spread. The results indicate that the disease-free steady state is unstable, raising substantial concern from the public health point of view. The results show that the fraction of newborns who fail to adhere to the HIV management guidelines (30%) significantly contributes to the spread of HIV. However, the rate of HIV-positive newborns under treatment therapy is significant. This study agrees that only a small proportion of HIV-positive newborns adhere to management guidelines. These analyses should yield significant knowledge to advance our understanding of HIV infection in the early stages of life.en_US
dc.publisherRoutledgeen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectHIV diseasesen_US
dc.subjectreproduction numberen_US
dc.subjectsensitivity analysisen_US
dc.subjecttransmission mathematical modelingen_US
dc.subjecttreatment therapyen_US
dc.titleA mathematical model of how non-adherence to HIV management guidelines for infected newborns contribute to the spread of HIV/AIDSen_US
dc.typeArticleen_US
dc.identifier.eissn1538151X
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalJournal of HIV/AIDS and Social Servicesen_US
dc.identifier.eid2-s2.0-85119136588
dc.identifier.scopusidSCOPUS_ID:85119136588
dc.source.volume20
dc.source.issue4
dc.source.beginpage379
dc.source.endpage391
dc.source.journaltitleJournal of HIV/AIDS and Social Services


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International