Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression.
dc.contributor.author | Brandt, Sabine | |
dc.contributor.author | Ballhause, Tobias M | |
dc.contributor.author | Bernhardt, Anja | |
dc.contributor.author | Becker, Annika | |
dc.contributor.author | Salaru, Delia | |
dc.contributor.author | Le-Deffge, Hien Minh | |
dc.contributor.author | Fehr, Alexander | |
dc.contributor.author | Fu, Yan | |
dc.contributor.author | Philipsen, Lars | |
dc.contributor.author | Djudjaj, Sonja | |
dc.contributor.author | Müller, Andreas J | |
dc.contributor.author | Kramann, Rafael | |
dc.contributor.author | Ibrahim, Mahmoud | |
dc.contributor.author | Geffers, Robert | |
dc.contributor.author | Siebel, Chris | |
dc.contributor.author | Isermann, Berend | |
dc.contributor.author | Heidel, Florian H | |
dc.contributor.author | Lindquist, Jonathan A | |
dc.contributor.author | Mertens, Peter R | |
dc.date.accessioned | 2022-06-13T08:23:25Z | |
dc.date.available | 2022-06-13T08:23:25Z | |
dc.date.issued | 2020-08-28 | |
dc.date.submitted | 2019-12-13 | |
dc.identifier.pmid | 32859670 | |
dc.identifier.doi | 10.1681/ASN.2019121289 | |
dc.identifier.uri | http://hdl.handle.net/10033/623201 | |
dc.description.abstract | Kidney injuries that result in chronic inflammation initiate crosstalk between stressed resident cells and infiltrating immune cells. In animal models, whole-body receptor Notch3 deficiency protects from leukocyte infiltration and organ fibrosis. However, the relative contribution of Notch3 expression in tissue versus infiltrating immune cells is unknown. | en_US |
dc.language.iso | en | en_US |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | cell adhesion | en_US |
dc.subject | cell signaling | en_US |
dc.subject | chronic inflammation | en_US |
dc.subject | chronic kidney disease | en_US |
dc.subject | fibrosis | en_US |
dc.title | Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression. | en_US |
dc.type | Article | en_US |
dc.identifier.eissn | 1533-3450 | |
dc.identifier.journal | Journal of the American Society of Nephrology : JASN | en_US |
dc.source.volume | 31 | |
dc.source.issue | 11 | |
dc.source.beginpage | 2589 | |
dc.source.endpage | 2608 | |
refterms.dateFOA | 2022-06-13T08:23:26Z | |
dc.source.journaltitle | Journal of the American Society of Nephrology : JASN | |
dc.source.country | United States |