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dc.contributor.authorEggert, Alina
dc.contributor.authorEtling, Christoph
dc.contributor.authorLübken, Dennis
dc.contributor.authorSaxarra, Marius
dc.contributor.authorKalesse, Markus
dc.date.accessioned2022-06-14T14:17:35Z
dc.date.available2022-06-14T14:17:35Z
dc.date.issued2020-08-24
dc.date.submitted2020-07-22
dc.identifier.pmid32847075
dc.identifier.doi10.3390/molecules25173841
dc.identifier.urihttp://hdl.handle.net/10033/623229
dc.description.abstractContiguous quaternary carbons in terpene natural products remain a major challenge in total synthesis. Synthetic strategies to overcome this challenge will be a pivotal prerequisite to the medicinal application of natural products and their analogs or derivatives. In this review, we cover syntheses of natural products that exhibit a dense assembly of quaternary carbons and whose syntheses were uncompleted until recently. While discussing their syntheses, we not only cover the most recent total syntheses but also provide an update on the status quo of modern syntheses of complex natural products. Herein, we review (±)-canataxpropellane, (+)-waihoensene, (-)-illisimonin A and (±)-11-O-debenzoyltashironin as prominent examples of natural products bearing contiguous quaternary carbons.en_US
dc.language.isoenen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectcanataxpropellaneen_US
dc.subjectnatural productsen_US
dc.subjectortho-photo-cycloadditionen_US
dc.subjecttaxane diterpeneen_US
dc.subjecttotal synthesisen_US
dc.subjectwaihoenseneen_US
dc.titleContiguous Quaternary Carbons: A Selection of Total Syntheses.en_US
dc.typeArticleen_US
dc.identifier.eissn1420-3049
dc.identifier.journalMolecules (Basel, Switzerland)en_US
dc.source.volume25
dc.source.issue17
refterms.dateFOA2022-06-14T14:17:35Z
dc.source.journaltitleMolecules (Basel, Switzerland)
dc.source.countrySwitzerland


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International