Show simple item record

dc.contributor.authorPeterson, John I.
dc.contributor.authorStefansson, Einar
dc.date.accessioned2023-08-30T09:16:00Z
dc.date.available2023-08-30T09:16:00Z
dc.date.issued1987
dc.date.submitted2023-08-30
dc.identifier.citationBiosensors International Workshop 1987, 235 - 241en_US
dc.identifier.isbn0-89573-683-7
dc.identifier.isbn3-527-26801-4
dc.identifier.issn0930-4320
dc.identifier.urihttp://hdl.handle.net/10033/623432
dc.description.abstractIn 1978 work was begun on development of a fiber optic oxygen partial pressure sensor for physiological application. Originally a search was made for an optical absorption indicator, but since one with suitable stability could not be found, a sensor was developed based on the fluorescence quenching principles demonstrated by Kautsky and Hirsch. The original sensor, based on a dye adsorbed on a hydrophobic support enclosed in a porous envelope, has been further developed into a needle form for physiological research applications. Instrumentation to use the sensor has followed an evolutionary path. The principal problem has been to obtain low drift and good stability of the calibration. A computer operated instrument has just been completed, which is expected to be suitable for a variety of research applications. A series of experiments to measure PO, in dogs' eyes were done with a prototype instrument in comparison with a polarographic electrode, and future work on human subjects is planned with the new instrument. This requires operation of the sensor in a high ambient light level. The instrumentation and measurements will be described.en_US
dc.language.isoenen_US
dc.publisherGBF - Gesellschaft für Biotechnologische Forschungen_US
dc.relation.ispartofseriesGBF Monographs, Volume 10en_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleFIBER OPTIC OXYGEN SENSORen_US
dc.typeBook chapteren_US
dc.typeconference paperen_US
dc.contributor.departmentBiomedical Engineeering and Instrumentation Branch Division of Research Services National Institutes of Health Bethesda Maryland 20892 * Assistant Professor Department of Ophthalmology DUKE UNIVERSITY MEDICAL CENTER Durham North Carolina 27710en_US
dc.identifier.journalBiosensors International Workshop 1987en_US
refterms.dateFOA2023-08-30T09:16:02Z


Files in this item

Thumbnail
Name:
Peterson235.pdf
Size:
3.782Mb
Format:
PDF
Description:
PDF

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-ShareAlike 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International