MEASUREMENT OF SUBCUTANEOUS GLUCOSE CONCENTRATION IN SHEEP WITH AN AMPEROMETRIC ENZYME ELECTRODE

Abstract

An amperometric enzyme electrode was developped for measurement of glucose in subcutaneous tissue. In vitro, this sensor exhibited an linear range extending to 500 mg/dl and was stable for at least 7 days. The measurement was relatively independent from ambient oxygen concentrations and was not significantly influenced by stirring. In short term in vivo experiments this sensor was successfully used for glucose measurement in subcutaneous tissue of sheep.