A DISPOSABLE OPTICAL BIOSENSOR BASED ON TOTAL INTERNAL REFLECTION FLUORESCENCE

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Authors
Sutherland, R.
Frevert, J.
Place, J. F.
Knoell, H.
Bregnard, A.
Dähne, C.
Revillet, G.
Hybl, E.
Issue Date
1987
Submitted date
2023-09-06

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Abstract
A novel disposable biosensor device is described, based on the generation of evanescent light waves at an optical interface. The sensor is injection moulded from high optical quality plastic and consists of two parts, the waveguide and a cuvette for containing the sample solution. Antigens are attached to the waveguide surface and the reaction with antibodies is monitored by exciting and collecting fluorescent light "back-tunneled" out of the waveguide. A model assay for human IgG is used to demonstrate that this biosensor can give rapid, sensitive results.
Citation
Biosensors International Workshop 1987, 305 - 306
Affiliation
BATTELLE-EUROPE, 1Geneva and Frankfurt Laboratories
Publisher
GBF - Gesellschaft für Biotechnologische Forschung
Journal
Biosensors International Workshop 1987
URI
http://hdl.handle.net/10033/623455
Type
Book chapter
conference paper
Language
en
Series/Report no.
GBF Monographs, Volume 10
ISSN
0930-4320
ISBN
0-89573-683-7
3-527-26801-4
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Attribution-NonCommercial-ShareAlike 4.0 International
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