AN OPTICAL BIOSENSOR FOR THE DETECTION OF A BACTERIAL TOXIN

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Authors
Frevert, J.
Werner, K.
Knoell, H. E.
Issue Date
1989
Submitted date
2024-01-16

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Abstract
The EVIA-biosensor (evanescent wave immunoassay) was evaluated for the determination of botulinum toxin. Three different assay systems were used: an inhibition type assay using fluorescent labelled antibody, a fluorescent excitation transfer immunoassay with rhodamine labelled antibodies as quenchers and a sandwich type immunoassay. The inhibition type assay system proved to be highly suitable for this sensor technique. 200 ng of the toxin could be detected.
Citation
Biosensors : applications in medicine, environmental protection and process control, 267 - 270
Affiliation
Battelle-Institut e.V., Am Römerhof35, 6000 Frankfurt 90
Publisher
GBF Gesellschaft für Biotechnologische Forschung mbH, Braunschweig
Journal
Biosensors : applications in medicine, environmental protection and process control, 1989
URI
http://hdl.handle.net/10033/623579
Type
Book chapter
conference paper
Language
en
Series/Report no.
GBF monographs ; Volume 13
ISSN
0930-4320
ISBN
3527280324
0895739550
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International