MEASUREMENT OF THE ACCUMULATION OF BIOMOLECULES IN A SOLUTION BY MEANS OF PIEZOELECTRIC CRYSTALS

Abstract

The principle of micro weighingis used to detect minute amounts of biological and chemical substances in liquids. By this micro weighing mass accumulation onto a sensitive layer can be measured,e. g. the accumulation of antigens onto a layer of antibodies. This paper deals with micro weighing based on the principle of measuring the change of the resonant frequency of a piezoelectric resonator in consequence of the above-mentioned mass accumulation.