IMAGING OF LASER-INDUCED FLUORESCENCE EMITTED BY TUMOR LOCALIZING PHOTOSENSITIZERS
Abstract
Photodynamic therapy is an experimental modality for the destruction of tumors or tumor cells by photochemical processes /1,2/. Such reactions are induced by exciting tumor-localizing photosensitizers by visible laser light. In addition to therapeutical applications, the characteristic fluorescence of the excited photosensitizers can be used for diagnostic purposes, i.e. for localization and imaging of tumors. The detection of small tumors as well as the determination of the extent of the lesion sensitively depend on the discrimination between sensitizer and tissue autofluorescence. This is particularly important at the boundary between tumor and normal tissue.Citation
Biosensors : applications in medicine, environmental protection and process control, 385 - 387Affiliation
Physikalisch-Technische Bundesanstalt, Institut Berlin AbbestraBe 2-12, D - 1000 Berlin 10; Freie Universität Berlin, Institut für Toxikologie und Embryonalpharmakologie Garystraße 5, D - 1000 Berlin 33Type
Book chapterconference paper
Language
enSeries/Report no.
GBF monographs ; Volume 13ISSN
0930-4320ISBN
35272803240895739550
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