USE OF CRYSTALLINE BACTERIAL SURFACE LAYERS(S-LAYERS) FOR THE DEVELOPEMENTOF BIOANALYTICAL SENSORS

Abstract

The developement of sensors for monitoring bioanalytical parameters has attracted much attention in medical, biotechnological and environmental applications. Although there are several different detection principles available now there is still enough innovation potential for developing alternative supports as immobilization matrices for biologically active component(s). Aside from the well established carriers such as synthetic polymer matrices, carbon, gold or platinum electrodes crystalline bacterial surface layers (S-layers) are an important alternative since they have shown an unsurpassed high and accurate binding capacity for a broad spectrum of enzymes (1).