Algorithmic Representation of Large RNA Folding Landscapes

Grüner, Walter; Giegerich, Robert; Strothmann, Dirk

dc.contributor.author	Grüner, Walter
dc.contributor.author	Giegerich, Robert
dc.contributor.author	Strothmann, Dirk
dc.date.accessioned	2024-05-29T09:10:02Z
dc.date.available	2024-05-29T09:10:02Z
dc.date.issued	1995
dc.date.submitted	2024-05-29
dc.identifier.citation	Bioinformatics - from nucleic acids and proteins to cell metabolism, 59 - 71	en_US
dc.identifier.isbn	3527300724
dc.identifier.issn	0930-4320
dc.identifier.uri	http://hdl.handle.net/10033/623850
dc.description.abstract	In evolutionary processes on the molecularlevel, neutral alterations play an important role [Kim83]. The primary sequence of a DNA or RNA moleculeis changed by errors introduced by the replication machinery at certain rates. Such a mutation does not necessarily affect the phenotype. The molecule’s contribution to the individual’s overall fitness is mediated by its function. For non-encoding RNA, the function in turn is determined by the 3D-structure of the molecule. A mutation in the primary sequence of such an RNA molecule that does notalter its structure is called neutral.	en_US
dc.language.iso	en	en_US
dc.publisher	GBF Gesellschaft für Biotechnologische Forschung mbH, Braunschweig	en_US
dc.relation.ispartofseries	GBF monographs ; Volume 18	en_US
dc.rights	Attribution-NonCommercial-ShareAlike 4.0 International	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/	*
dc.title	Algorithmic Representation of Large RNA Folding Landscapes	en_US
dc.type	Book chapter	en_US
dc.type	conference paper	en_US
dc.contributor.department	Institut für Molekulare Biotechnologie, Beutenbergstrasse 1, D-07708 Jena, Germany; Technische Fakultät, Univ. Bielefeld, Postfach 10 01 31, D-33501 Bielefeld, Germany	en_US
dc.identifier.journal	Bioinformatics - from nucleic acids and proteins to cell metabolism, 1995	en_US
refterms.dateFOA	2024-05-29T09:10:04Z